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CellProfiler: image analysis software for identifying and quantifying cell phenotypes

Anne E. Carpenter; Thouis R. Jones; Michael R. Lamprecht; Colin Clarke; In Han Kang; Ola Friman; David A. Guertin; Joo Han Chang · Genome biology · 2006

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Author / responsible party
Anne E. Carpenter; Thouis R. Jones; Michael R. Lamprecht; Colin Clarke; In Han Kang; Ola Friman; David A. Guertin; Joo Han Chang
Publisher
Genome biology
Year
2006
Language
English

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Biologists can now prepare and image thousands of samples per day using automation, enabling chemical screens and functional genomics (for example, using RNA interference). Here we describe the first free, open-source system designed for flexible, high-throughput cell image analysis, CellProfiler. CellProfiler can address a variety of biological questions quantitatively, including standard assays (for example, cell count, size, per-cell protein levels) and complex morphological assays (for example, cell/organelle shape or subcellular patterns of DNA or protein staining).

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APA 7

Carpenter, A. E, Jones, T. R, Lamprecht, M. R, Clarke, C, Kang, I. H, Friman, O, Guertin, D. A, & Chang, J. H. (2006). CellProfiler: image analysis software for identifying and quantifying cell phenotypes. https://doi.org/10.1186/gb-2006-7-10-r100

MLA

Carpenter, Anne E, et al. "CellProfiler: image analysis software for identifying and quantifying cell phenotypes." 2006. https://doi.org/10.1186/gb-2006-7-10-r100.

Chicago

Carpenter, Anne E, Thouis R. Jones, Michael R. Lamprecht, Colin Clarke, In Han Kang, Ola Friman, David A. Guertin, and Joo Han Chang. 2006. "CellProfiler: image analysis software for identifying and quantifying cell phenotypes.". https://doi.org/10.1186/gb-2006-7-10-r100.

Harvard

Carpenter, A. E. et al. 2006, CellProfiler: image analysis software for identifying and quantifying cell phenotypes, Genome biology, available at: https://doi.org/10.1186/gb-2006-7-10-r100 [Accessed 8 Aug. 2026].

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Title
CellProfiler: image analysis software for identifying and quantifying cell phenotypes
Author / contributors
Anne E. Carpenter; Thouis R. Jones; Michael R. Lamprecht; Colin Clarke; In Han Kang; Ola Friman; David A. Guertin; Joo Han Chang
Publisher
Genome biology
Publication year
2006
Language
English

Subjects

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Biology; Human genetics; Computational biology; Phenotype; Evolutionary biology; Genome Biology; Software; Genetics; Bioinformatics; Genomics; Genome; Computer science
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