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BackgroundSepsis-induced cardiomyopathy (SCM) is a common complication in patients with sepsis. Although the prognostic nutritional index (PNI) is less comprehensive than other assessment methods, it remains a readily ac...

Sepsis remains a major challenge in critical care medicine worldwide, characterized by a dynamic imbalance of the immune system between two extremes: “immunoparalysis” and “hyperactivation.” This dysregulation se...

Objective This study aimed to explore the influence of the angiotensin-(1–7)/Mas receptor and angiotensin II/angiotensin II type 1 receptor pathways on pyroptosis during sepsis and their subsequent effects on cognitive...

Abstract Septic cardiomyopathy (SC) is a severe complication of sepsis that significantly increases patient mortality. The onset of SC is associated with excessive reactive oxygen species (ROS), leading to increased oxid...

Background and AimsThe immune response to an infectious agent is regulated by a complex network of signaling pathways involving numerous genes encoding inflammatory mediators, proteins of the innate and adaptive immune s...

Abstract Background Antimicrobial treatment protocols for foals with sepsis that do not improve clinically often are adjusted based on bacteriological and antimicrobial susceptibility testing results from samples collect...

BackgroundPredicting enterocutaneous fistula (ECF)–associated sepsis and mortality poses significant challenges in digital health care due to the disease’s complexity and heterogeneous clinical manifestations. Curren...

ABSTRACT Background The glutaraldehyde test (GT) is used as a point‐of‐care test to detect inflammatory disease in cattle. Objectives Describe the relationship between GT and fibrinogen as well as GT and total protei...

Background and AimsAcquired immunodeficiency in patients with hematological oncology is a serious and common complication, significantly impacting prognosis and quality of life. High doses of cytostatic drugs and the mal...

Sepsis remains one of the most complex and lethal syndromes in pediatric critical care, driven by dysregulated and heterogeneous host responses to infection. Despite decades of biomarker research, few biomarkers have bee...

Abstract Background Sepsis is a life-threatening condition characterized by uncontrolled inflammation, oxidative stress, and aberrant cell death. Although the STING pathway is well established as a central mediator of in...

Background Puerperal sepsis remains a preventable contributor to maternal illness. Pregnancy-related sepsis is responsible for ∼10% to 15% of maternal deaths. Despite this burden, no comprehensive review has examined s...

Background and AimsSepsis is a common complication in patients with hematological malignancies that occurs during chemotherapy treatment, which in turn leads to acquired immunodeficiency. In recent years, increasing atte...

Background Dermatologic infections complicated by sepsis represent a significant yet understudied cause of mortality in the United States, with evolving epidemiological patterns that warrant investigation. Objective To e...

Sepsis-induced cardiomyopathy (SICM) develops in up to 60% of patients with sepsis, substantially increases mortality, and currently lacks specific pharmacotherapy. N6-methyladenosine (m6A), the most prevalent internal m...

Abstract Objective To study the structure ofmaternalmortality caused by abortion in the Tula region. Methods The medical records of deceased pregnant women, childbirth, and postpartum from January 01, 2001, to Decemb...

Abstract Background Improved methodology to measure acute phase proteins and determination of lipoprotein particle‐size distribution (PSD) could be clinically useful in dogs with systemic inflammatory processes. Object...

Abstract Background Bacterial sepsis is the leading cause of death in foals and is associated with hypothalamic‐pituitary‐adrenocortical axis (HPAA) dysfunction. HPAA function can be evaluated by an arginine‐vasopr...

Abstract Background Lameness is an economically important and common disease of cattle, and foot disease is the most common cause of lameness in cattle. Limited data is available regarding lameness in cow‐calf operatio...

Opioids remain central to managing moderate to severe pain, yet they also produce significant and often under-recognized effects on the immune system. In this narrative review, we synthesize evidence from 1994 to 2025 ac...

Introduction: Neonatal Conjugated Hyperbilirubinaemia (CHB) poses a significant diagnostic challenge in day to day practice because of its varied aetiologies with non-specific clinical presentations. The rationale of the...

Abstract Background Ascorbic acid (AA) is an antioxidant that might be beneficial for adjunctive treatment of sepsis in horses. The optimal dose and effects on oxidative status are unknown. Hypothesis Ascorbic acid admin...

Abstract Background The guidelines for treatment of patients with severe infection or sepsis do not include the indications for endotracheal intubation, nor do they address DNAR/DNI orders. Methods We aimed to describe t...

Enterocutaneous fistulas (ECFs) are among the most devastating complications in surgical practice. Management requires a multidisciplinary approach focused on sepsis control, nutritional optimization, fistula closure, an...