Buscar recursos académicos

ABSTRACT Zinc is a critical nutrient for all living organisms, including bacterial pathogens such as Corynebacterium diphtheriae, the causative agent of the severe human respiratory disease diphtheria. As such, zinc acqu...

The use of antibiotic growth promoters (AGPs) in poultry production has raised concerns for human, animal, and environmental health owing to the development and spread of antimicrobial resistance. These concerns have tri...

Abstract Current therapeutic approaches for colorectal cancer (CRC) face significant limitations, including drug resistance, adverse effects, and high costs. Autocrine motility factor (AMF), the extracellular form of glu...

Urbanization is considered an inevitable result of population growth in many developing countries. Cities attract migrants due to economic opportunities, infrastructure improvements, and higher living standards. However,...

Abstract Brain pericytes are mediators of neuroinflammation, as evidenced in vitro, in animal models and humans. We and others have identified the platelet-derived growth factor (PDGF)-BB -PDGF receptor beta (PDGFRB) pat...

In an era defined by the global transformation of the world order, characterized by a multitude of external and internal challenges, a new conceptual framework is advanced to steer the Russian economy toward a path of ba...

This study investigates how education, green technology, and clean energy function as explicit indicators of sustainability and ecological resilience in BRICS economies over the period 1995–2021. Moving beyond income-c...

El hexaclorobenceno (HCB) es un contaminante ambiental ampliamente distribuido y un desorganizador endocrino. Su exposición crónica en humanos produce porfiria, síntomas neurológicos, trastornos inmunitarios y disfun...

Space is an area that includes land space, sea space and air space, including space within the earth as a unified territory, where humans and other creatures live, carry out activities and maintain their survival. Increa...

Neste estudo, partindo-se de concepção do desenvolvimento como processo global (econômico, social e político), propõe-se formular modelos de intervenção pública em situações de pobreza, com o objetivo de supera...

Phenol is a toxic aromatic compound widely released into the environment through oil refineries, petrochemical industries, and industrial effluents, posing serious risks to ecosystems and human health. Given its persiste...

Heme oxygenase-1 (HO-1), which catalyzes heme degradation releasing iron, regulates several processes related to breast cancer. Iron metabolism deregulation is also connected with several tumor processes. However the reg...

The large-scale use of the herbicide glyphosate leads to growing ecotoxicological and human health concerns. Microbe-assisted phytoremediation arises as a good option to remove, contain, or degrade glyphosate from soils ...

The study investigates the Return on Investment (ROI) of Continuous Education (CE) initiatives in business organizations situated in the country of Georgia, focusing on their financial and non-financial impacts. Through ...

Introduction. Determining the benefits of basic human personality traits is one of the main components of the selection and staffing of small groups of peoples that are working in extreme environmental conditions and soc...

Nanobody-targeted photodynamic therapy (NB-PDT) has been developed as a potent and tumor-selective treatment, using nanobodies (NBs) to deliver a photosensitizer (PS) specifically to cancer cells. Upon local light applic...

Indonesia is experiencing a demographic transition phenomenon. This can be seen from the results of the 2010 population census, which showed a positive trend in the productive age population, namely 15-64 years. In that ...

Abstract Background Treatment of head and neck squamous cell carcinoma (HNSCC) remains challenging and the survival rates of affected patients remain poor. A three-dimensional organotypic co-culture (3D-OTC) model where ...

Photodynamic priming (PDP), a collateral effect of photodynamic therapy, can transiently alter the tumor microenvironment (TME) beyond the cytotoxic zone. Studies have demonstrated that PDP increases tumor permeability a...

IntroductionAquatic light environments are increasingly altered by human activity, yet the endocrine and molecular mechanisms enabling fish to cope with extreme photoperiods remain poorly understood. This study investiga...

Progesterone has long been linked to breast cancer but its actual role as a cancer promoter has remained in dispute. Previous in vitro studies have shown that progesterone is converted to 5a-dihydroprogesterone (5aP) in ...

Abstract Selenium (Se) enriched forest-grown ginseng is famous for its high Se content and excellent protein quality, which are necessary for varieties of metabolic processes and play an important role in both ginseng gr...

ABSTRACT In Bacillota, quorum sensing can be mediated by RRNPP regulators that are activated by autoinducing peptides (AIPs). In this study, we derived a hidden Markov model profile from a 3D-informed alignment to establ...

Abstract Cytokines from the transforming growth factor-β (TGF-β) superfamily are essential regulators of cell growth, survival, and differentiation, playing a pivotal role in mammalian embryonic development, adult tiss...