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Abstract This cross-sectional survey evaluated the knowledge, attitudes, and practices (KAP) of healthcare providers regarding transfusion-related acute lung injury (TRALI) in Jiangsu from March to May 2025. A self-admin...

Abstract Background Disruption of cellular proteostasis leads to the accumulation and persistence of pathogenic proteins that drive oncogenesis. Key oncogenic and tumor suppressor proteins are frequently dysregulated in ...

IntroductionDNGR-1 (CLEC9A), a C-type lectin receptor specifically expressed on human BDCA3+ and murine CD8α+/CD103+ conventional type 1 dendritic cells (cDC1), acts as a damage-associated molecular pattern (DAMP) recep...

Abstract Chronobiology has advanced scientifically since 2000. Translating this knowledge and approach to medicine can alter diagnosis, treatment, and prevention, and improve health. Adding time-of-day (or time-of-year) ...

BackgroundNon-dental healthcare professionals (NDHPs) play an important role in oral health promotion; however, evidence on their oral health knowledge, attitudes, and practices (KAP) remains limited. This study aimed to...

The traditional definition of retranslation as the second or later rendering of a work into one same language is necessarily transformed when seen from a perspective informed by multimodality and intermediality. While th...

Abstract Background In India’s tea-garden regions, including Darjeeling, geographical remoteness, socioeconomic hardship, and limited healthcare access constrain emergency response capacity. Mothers often serve as firs...

Malignant lung tumors are the leading cause of cancer-related mortality worldwide, and therefore remodeling of the tumor microenvironment (TME) has become an important strategy to overcome anti-tumor therapy resistance i...

ABSTRACT Background and Aims Patient and public involvement and engagement (PPIE) in research is crucial for producing knowledge that is meaningful to the participating community. Sharing PPIE principles into practical t...

Sign Language Translation (SLT) is fundamentally a process of intersemiotic translation, involving the transfer of meaning between visual-gestural and spoken language systems. However, most existing SLT studies focus on ...

Background: Nucleosomes are the building blocks of chromatin where gene regulation takes place. Chromatin landscapes have been profiled for several species, providing insights into the fundamental mechanisms of chromatin...

Small sample sizes in preclinical research limit the extraction of reliable knowledge and hinder translational progress. We propose genESOM, a generative artificial intelligence method based on emergent self‑organizing...

Abstract This is the protocol for a Campbell systematic review. The objectives are as follows: Our aim is to collect, assess, and synthesise all the available empirical evidence on what works to support evidence‐inform...

Yu Zhao,1,* Luting Wang,2,3,* Shengrui Zhu,4 Rui Feng,5 Wei Zhang1 1Geriatric Medicine Center, Department of Endocrinology, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzho...

Introduction There are national calls for reducing physician administrative burden. While interest in digital scribes (DS) is growing, there is limited evidence evaluating their safety and effectiveness. In contrast, hum...

Abstract Background Research capacity building programs facilitate clinician engagement with best-practice research. Benefits of research capacity in healthcare locations are far reaching, including individual community ...

Abstract Background Circadian rhythms are endogenous, transcription-translation feedback loops that align cellular activities with the 24-h light–dark cycle. Stem-cell populations across tissues exhibit circadian oscil...

Background. Viral infections remain a major global health threat despite advances in vaccines and antiviral drugs due to the rapid emergence of resistance and new viral pathogens. Antiviral peptides (AVPs) are promising ...

Abstract Astrocytes play key roles in maintaining brain homeostasis, metabolism, and neurovascular integrity, yet their diversity and age-related modulation remain insufficiently understood, particularly across primate l...

Abstract The rapid growth of biological resources and associated research outputs has increased the complexity of resource discovery, access, and reuse across heterogeneous repositories. However, fragmented metadata sche...

A gap between scientific research and regulatory frameworks continues to challenge the effective translation of science into policy and regulation. This commentary explores the disconnection between scientific research, ...

Abstract To support the efforts of urban experimentation spaces, such as testbeds and living labs, in accelerating societal transformations towards urban sustainability, an exchange of experiences and knowledge across lo...

T follicular helper (Tfh) cells have been reported to have multiple trajectories, including terminally differentiated Tfh, memory-like circulatory Tfh (cTfh), and, most recently, induced T follicular regulatory (iTfr) ce...

Abstract Introduction Enterovirus A71 (EV71)–associated encephalitis lacks targeted neuroprotective therapy. Experimental data implicate endoplasmic reticulum (ER) stress and ferroptosis in neuronal injury. We tested w...