Buscar recursos académicos

The nematode Caenorhabditis elegans is an established model organism for studying neurobiology. UNC-63 is a C. elegans nicotinic acetylcholine receptor (nAChR) α-subunit. It is an essential component of the levamisole-s...

Abstract Heart failure (HF) is a common disease resulting in high morbidity, mortality, and healthcare costs. An important cause of HF is mitral valve regurgitation (MR), which induces left ventricular remodeling and vol...

Abstract Background Autoantibody biomarkers are valuable tools used to diagnose and manage autoimmune diseases in dogs. However, prior publications have raised concerns over a lack of standardization and sufficient valid...

Abstract Background Treatment is indicated in dogs with preclinical degenerative mitral valve disease (DMVD) and cardiomegaly (stage B2). This is best diagnosed using echocardiography; however, relying upon this limits a...

Abstract Acquired cervical scoliosis previously has been reported in dogs as a clinical sign associated with Chiari‐like malformation and syringomyelia but has not been described with inflammatory central nervous syste...

Abstract High cardiorespiratory fitness and exercise show evidence of altering bile acid (BA) metabolism and are known to protect or treat diet-induced hepatic steatosis, respectively. Here, we tested the hypothesis that...

An increased permeability of the intestinal barrier is proposed as a major event in the pathophysiology of conditions characterized by chronic gut inflammation. This study investigated the capacity of pure anthocyanins (...

Objective. To assess non-participation bias in a survey ofmale sexual behavior. Material and methods. A householdsurvey was carried out in 1992-1993 using a probabilitysampling frame in Mexico City. Demographic variables...

We used and evaluated the effectiveness of a hand-capture technique to capture and mark neonatal vicuñas (Vicugna vicugna) at San Guillermo National Park, west-central Argentina. We captured and marked 98 neonates durin...

Abstract Brain pericytes are mediators of neuroinflammation, as evidenced in vitro, in animal models and humans. We and others have identified the platelet-derived growth factor (PDGF)-BB -PDGF receptor beta (PDGFRB) pat...

Introduction: Low-voltage electrical injuries are generally considered low risk but can cause significant thermal injury when current is concentrated through conductive materials. Circumferential neck burns from mobile p...

Abstract Background Limited recent data exists regarding discospondylitis in dogs. Hypothesis/Objectives (i) Describe the signalment, clinical and imaging findings, etiologic agents, treatment, and outcome of dogs with d...

Abstract Background DNA methylation analysis provides a promising triage strategy for cervical intraepithelial neoplasia (CIN) and cancer detection following Human Papillomavirus (HPV) testing on self-collected samples, ...

Abstract Chronic wound analysis is crucial for effective wound care, necessitating precise and efficient segmentation techniques. This study explores the use of YOLOv8 and YOLO11, renowned deep learning algorithms for ob...

ABSTRACT Background The comparative effectiveness of radiotherapy and surgery for treating intracranial meningioma is unknown. Objectives To compare survival after treatment of suspected intracranial meningioma by either...

Abstract This study provides a comprehensive dataset (FAIRUrbTemp) that addresses the lack of high-resolution urban air temperature data across Europe. It compiles sub-hourly street-level air temperature data from 811 lo...

Abstract A 2‐year‐old female spayed dog was presented with a chronic history of short‐strided gait and inability to completely open the jaw. Clinical signs were present since the dog was adopted from a humane socie...

Abstract Background As dementia cases continue to rise, effective prevention strategies are urgently needed. However, objective biomarkers that directly reflect lifestyle factors remain limited. Life’s Essential 8 (LE8...

Abstract Background Long COVID is an infection-associated chronic condition with uncertain evolution, leading to ambiguity in case definitions and various hypotheses about its pathophysiology. Despite this diversity, cau...

Abstract Background Endothelial cells (ECs) orchestrate vascular homeostasis and resilience but can undergo reprogramming into a mesenchymal-like phenotype through an endothelial-to-mesenchymal transition (EndMT). Crucia...

Abstract Background Cardiac disease is an important cause of morbidity and mortality in Irish Wolfhounds (IWs), but its prevalence and clinical characteristics in North American IWs are incompletely described. Hypothesis...

Abstract Purpose Intraoperative radiotherapy (IORT) is designed to deliver a precise dose of ionizing radiation to a tumor or tumor bed after surgical resection. The IORT procedure can deliver targeted radiation to the t...

The Dinaledi Chamber of the Rising Star cave system has yielded a large assemblage of fossil hominin material, attributed to Homo naledi. The unusual taphonomic and geological situation of the assemblage suggested that t...