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120 resultados encontrados.

Tipos de recurso: Libro electrónico Artículo Revista Tesis Capítulo
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Evaluation of randomized controlled trial literature in traditional Chinese medicine: a literature quality assessment system
Artículo
Acceso abierto Artículo DOAJ
Yunan Zhang et al · BMC · 2026 · ISSN 1745-6215
Abstract Background Previous studies have evaluated traditional Chinese medicine (TCM) clinical randomized controlled trial (RCT) literature broadly, but they have provided limited depth in evaluating the specific aspect...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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Open Access
Mindful self-compassion to reduce stigma among individuals diagnosed with lung cancer (MSC-LC): a pilot study protocol for a parallel-group, randomized controlled trial
Artículo
Acceso abierto Artículo DOAJ
Timothy J. Williamson et al · BMC · 2026 · ISSN 2055-5784
Abstract Background Lung cancer stigma (i.e., perceived and internalized negative appraisal and devaluation associated with lung cancer) is a clinically significant psychosocial concern among individuals diagnosed with l...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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Open Access
Talking Mats and self-perceived involvement for service recipients with dementia in Swedish home care services: a randomized controlled trial
Artículo
Acceso abierto Artículo DOAJ
Angela Bångsbo et al · BMC · 2026 · ISSN 1471-2318
Abstract Background Older people with dementia are regularly excluded from decision-making processes and their wishes and preferences for care are often not respected. The aim of this study was to analyze whether the use...
LCC TENDOkdlcmlhdHJpY3M~Idioma eng
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Open Access
The Impact of Early Clinical Exposure on Competency Development in Dental Students: A Systematic Review and Meta-Analysis
Artículo
Acceso abierto Artículo DOAJ
Xuefei Pang et al · Elsevier · 2026 · ISSN 0020-6539
Introduction and aims: Early clinical exposure (ECE) integrates students into clinical settings during theoretical learning, aiming to foster professional development. This systematic review aims to comprehensively evalu...
LCC TENDOkRlbnRpc3RyeQ~~Idioma eng
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Open Access
Understanding trial informativeness in digital mental health: perspectives from researchers and lived experience experts
Artículo
Acceso abierto Artículo DOAJ
Alexia Jeayes et al · BMC · 2026 · ISSN 1745-6215
Abstract Background Randomised controlled trials (RCTs) are often considered the gold standard in research design to determine clinical and cost-effectiveness, and yet the majority are not considered “informative” or...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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Open Access
Artificial pancreas: clinical study in Latin America without premeal insulin boluses
Texto / recurso
Acceso abierto Texto / recurso RI ITBA
Sánchez-Peña, Ricardo et al · RI ITBA · 2019 · ISSN 1932-2968
"Background: Emerging therapies such as closed-loop (CL) glucose control, also known as artificial pancreas (AP) systems, have shown significant improvement in type 1 diabetes mellitus (T1DM) management. However, demandi...
Idioma en
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Open Access
Combined Sertraline and Naltrexone in Online Gambling Disorder with Comorbid Depression: A Three-Case Clinical Report
Artículo
Acceso abierto Artículo DOAJ
Halil Ibrahim Eren et al · Van Yuzuncu Yil University, School of Medicine · 2026 · ISSN 2587-0351
Introduction: Online Gambling Disorder is an increasingly prevalent behavioral addiction frequently accompanied by depressive symptoms and significant functional impairments. Despite growing clinical recognition, pharmac...
LCC LCC:MedicineIdioma eng
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Open Access
Development of a Patient Decision Aid for the DAHANCA 35 Proton Radiotherapy Trial: An Iterative Development Process with User-Centered Design Elements
Artículo
Material complementario disponible Artículo DOAJ
Anne Wilhøft Kristensen et al · SAGE Publishing · 2026 · ISSN 2381-4683
Background. Deciding whether to participate in a radiotherapy trial is complex for patients with head and neck cancer. Standard patient information leaflets meet ethical requirements but do not provide balanced compariso...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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Material complementario
Digital treatment for insomnia in adolescents: study protocol for a randomized controlled trial comparing digital cognitive behavioral therapy for insomnia to sleep hygiene
Artículo
Acceso abierto Artículo DOAJ
Beke Ralfs et al · Frontiers Media S.A · 2026 · ISSN 2813-4540
BackgroundInsomnia is highly prevalent among adolescents. It is associated with various mental and physical disorders and impairments in daytime functioning. Cognitive behavioral therapy for insomnia (CBT-I) is well supp...
LCC TENDOlBzeWNoaWF0cnk~; TENDOlBlZGlhdHJpY3M~Idioma eng
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Open Access
Effect of gradually increasing force magnitude on the rate of canine retraction: a split mouth randomized controlled trial
Artículo
Acceso abierto Artículo DOAJ
Shady Abd El-Salam et al · BMC · 2026 · ISSN 1472-6831
Abstract Objective To evaluate the effect of gradually increasing orthodontic force magnitude compared with a constant force magnitude on the rate of tooth movement during maxillary canine retraction. Methods This split-...
LCC TENDOkRlbnRpc3RyeQ~~Idioma eng
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Open Access
Effect of multicomponent exercise intervention on older adults with mild cognitive impairment based on HAPA-TPB theory (MIND-STEP): trial design and baseline data for a randomized controlled trial
Artículo
Material complementario disponible Artículo DOAJ
Na Zhang et al · BMC · 2026 · ISSN 1745-6215
Abstract Background Physical exercise has emerged as a promising non-pharmacological approach for improving cognitive and physical function in older adults with mild cognitive impairment (MCI). However, most existing int...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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Material complementario
Effects of aerobic exercise on vascular endothelial function and markers of oxidative stress and inflammation in individuals with impaired glucose tolerance: study protocol for a randomized controlled trial
Artículo
Acceso abierto Artículo DOAJ
Hancheng Wu et al · Frontiers Media S.A · 2026 · ISSN 1664-2392
Background and objectiveEndothelial dysfunction is a key driver of cardiovascular complications in individuals with impaired glucose tolerance (IGT), with oxidative stress and inflammation playing pivotal roles in its pa...
LCC LCC:Diseases of the endocrine glands. Clinical endocrinologyIdioma eng
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Open Access
Effects of blood flow restriction combined with robot-assisted training on upper limb motor function after stroke: a randomized controlled trial protocol
Artículo
Material complementario disponible Artículo DOAJ
Qian Zhang et al · Frontiers Media S.A · 2026 · ISSN 1664-2295
BackgroundUpper limb motor dysfunction is common after stroke and substantially restricts independence. Robot-assisted training (RAT) and blood flow restriction training (BFRT) have individually demonstrated potential be...
LCC LCC:Neurology. Diseases of the nervous systemIdioma eng
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Health-related quality of life in immunocompromised adults with mild–moderate COVID-19 treated with nirmatrelvir-ritonavir: results from the randomized, double-blinded EPIC-IC trial
Artículo
Acceso abierto Artículo DOAJ
Ruth Mokgokong et al · BMC · 2026 · ISSN 1477-7525
Abstract Background Little is known about health-related quality of life (HRQoL) in immunocompromised people during and after COVID-19 illness. We describe HRQoL outcomes from the EPIC-IC trial, which included participan...
LCC TENDOkNvbXB1dGVyIGFwcGxpY2F0aW9ucyB0byBtZWRpY2luZS4gTWVkaWNhbCBpbmZvcm1hdGljcw~~Idioma eng
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Open Access
Impact of a structured nurse-delivered multi component SGLT2 inhibitor initiation and optimization pathway on kidney function and clinical outcomes in type 2 diabetes and chronic kidney disease: a real-world retrospective study
Artículo
Acceso abierto Artículo DOAJ
Liang Huang et al · BMC · 2026 · ISSN 1471-2369
Abstract Background The implementation gap between evidence-based SGLT2 inhibitor therapy and real-world practice remains substantial in patients with type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD). Pro...
LCC TENDOkRpc2Vhc2VzIG9mIHRoZSBnZW5pdG91cmluYXJ5IHN5c3RlbS4gVXJvbG9neQ~~Idioma eng
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Open Access
Improved quality of life, reduced quantitative lung fibrosis in a trial of inhaled pirfenidone for idiopathic pulmonary fibrosis
Artículo
Material complementario disponible Artículo DOAJ
Grace Hyun J. Kim et al · BMC · 2026 · ISSN 1471-2466
Abstract Background AP01, a novel formulation of inhaled pirfenidone, has demonstrated potential for improved efficacy and safety for idiopathic pulmonary fibrosis (IPF) vs. oral pirfenidone. A 72-week phase 1b study, AT...
LCC TENDOkRpc2Vhc2VzIG9mIHRoZSByZXNwaXJhdG9yeSBzeXN0ZW0~Idioma eng
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Intraoperative endoscopic pylorus dilatation during minimally invasive Ivor Lewis oesophagectomy to prevent delayed gastric conduit emptying (DGCE): protocol for the WIDE randomised controlled trial
Artículo
Acceso abierto Artículo DOAJ
Jennifer M Klasen et al · BMJ Publishing Group · 2026 · ISSN 2044-6055
Introduction Oesophageal cancer has a poor prognosis and oesophagectomy has increasingly adopted minimally invasive techniques, but delayed gastric conduit emptying (DGCE) still occurs in ~10–50% of patients, depending...
LCC LCC:MedicineIdioma eng
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Open Access
Lateral intubation with the Macintosh laryngoscope and C-MAC D blade videolaryngoscope (LATIN): A randomized controlled trial
Artículo
Acceso institucional disponible Artículo DOAJ
Renjith Viswanath, MD et al · Elsevier · 2026 · ISSN 1658-3612
الملخص: أهداف البحث: يُعدّ التنبيب الجانبي إجراء شائعا خارج غرف العمليات، لا سيما في عمليات التنظير الداخلي. تشمل التحدي...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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Institucional
Machine Learning Prediction and Reducing Overdoses With Electronic Health Record Nudges (mPROVEN) in the Primary Care Setting: Protocol for a Cluster Randomized Controlled Trial
Artículo
Material complementario disponible Artículo DOAJ
Walid F Gellad et al · JMIR Publications · 2026 · ISSN 1929-0748
BackgroundOpioid overdose remains a leading cause of preventable death in the United States. Existing approaches to identify individuals at elevated risk rely on imprecise rule-based criteria that misclassify patients’...
LCC LCC:Medicine; TENDOkNvbXB1dGVyIGFwcGxpY2F0aW9ucyB0byBtZWRpY2luZS4gTWVkaWNhbCBpbmZvcm1hdGljcw~~Idioma eng
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Optimizing colorectal cancer screening through polygenic risk score-based risk stratification: evidence from a population-based cohort and screening trial
Artículo
Acceso abierto Artículo DOAJ
Hongda Chen et al · BMC · 2026 · ISSN 1756-994X
Abstract Background Accurate risk stratification of colorectal cancer (CRC) is essential for precise screening. Polygenic risk scores (PRS) hold promise for improving predictive efficacy in CRC. However, the real-world a...
LCC LCC:Medicine; LCC:GeneticsIdioma eng
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Open Access
Perfil clínico, laboratorial e complicações de pacientes com síndrome HELLP admitidas em uma unidade de terapia intensiva obstétrica Clinical and laboratorial profile and complications of patients with HELLP syndrome admitted in an obstetric intensive care unit
Artículo
Acceso abierto Artículo DOAJ
Leila Katz et al · Federação Brasileira das Sociedades de Ginecologia e Obstetrícia · 2008 · ISSN 0100-7203
OBJETIVO: descrever o perfil clínico e laboratorial e complicações de pacientes com síndrome HELLP internadas em Unidade de Terapia Intensiva (UTI) obstétrica e incluídas em um ensaio clínico randomizado para aval...
LCC TENDOkd5bmVjb2xvZ3kgYW5kIG9ic3RldHJpY3M~Idioma eng
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Open Access
Propolis Supplementation and Metabolic Syndrome Components in Adults at Risk: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials
Artículo
Material complementario disponible Artículo DOAJ
Safia Obaidur Rab et al · Wiley · 2026 · ISSN 2398-8835
ABSTRACT Background and Aims Propolis is a natural resinous substance produced by bees, recognized for its antioxidant and anti‐inflammatory properties. Previous clinical trials have reported inconsistent results regar...
LCC LCC:MedicineIdioma eng
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Study on the effect of aquatic exercise combined with hot spring bathing for patients with chronic low back pain: a randomized controlled trial
Artículo
Material complementario disponible Artículo DOAJ
Lingli Qin et al · BMC · 2026 · ISSN 2052-1847
Abstract Background Chronic low back pain (CLBP) is a common musculoskeletal symptom associated with spinal disorders, impairing quality of life while imposing significant medical and socioeconomic burdens. Traditional l...
LCC TENDOlNwb3J0cyBtZWRpY2luZQ~~Idioma eng
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The independent and combined effect of price increase and price labelling on sugar-sweetened beverage vending machine sales in an Australian university: a factorial randomised controlled trial
Artículo
Acceso abierto Artículo DOAJ
Miranda R. Blake et al · BMC · 2026 · ISSN 1479-5868
Abstract Background No studies have examined how price increases on unhealthy drinks in university vending machines impact customer purchasing or vendor financial implications. Vending machines often display prices only ...
LCC LCC:Nutritional diseases. Deficiency diseases; LCC:Public aspects of medicineIdioma eng
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Open Access