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Understanding how laser pulses compress solids into high-energy-density states requires diagnostics that simultaneously resolve macroscopic geometry and nanometer-scale structure. Here we present a combined X-ray imaging...

Language and action systems are functionally coupled in the brain as demonstrated by converging evidence using Functional magnetic resonance imaging (fMRI), electroencephalography (EEG), transcranial magnetic stimulation...

Abstract This multicenter, first-in-human Phase 1 study (NCT04956640) evaluated olomorasib (LY3537982), a next-generation KRAS G12C inhibitor designed to enhance target occupancy at low absolute exposures. In total, data...

Chip-scale integrated optical signal processors promise to support a multitude of signal processing functions with bandwidths beyond the limit of microelectronics. Previous research has made great contributions in terms ...

Abstract Objective The coronavirus disease 2019 (COVID-19) is a pandemic viral disease, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The impact of the disease among the obstetric population r...

Resumo Os transtornos psiquiátricos possuem grande morbidade entre estudantes universitários da área da saúde. A depressão e ansiedade são os mais frequentes. O artigo se propõe a analisar os diferentes graus da d...

When microspheres are illuminated by tightly focused vortex beams, they can be trapped in a non-equilibrium steady state where they orbit around the optical axis. By using the Mie–Debye theory for optical tweezers, we ...

The Andean Bear is classified as ‘Vulnerable’ by the IUCN Red List of Threatened Species. Unfortunately, there is still a lack of data on the species’ reproduction and reproductive pathologies. General anesthesia w...

Current management does not fully prevent arrhythmias in long QT syndrome (LQTS), underscoring a need for novel therapies. Here, we investigated potential beneficial effects of serum/glucocorticoid-regulated-kinase-1 (SG...

O efeito da aplicação de diferentes doses de hCG sobre a emergência de nova onda de crescimento folicular e o número de folículos recrutados dessa onda, a formação de corpo lúteo acessório, o diâmetro do folíc...

Abstract Despite rising government health expenditure with significant challenges facing the health sector, Nigeria carries one of Africa’s highest malaria burdens which have been a primary cause of rising infant and m...

Catalytic methane decomposition (CMD) offers a direct pathway to CO2-free hydrogen by converting CH4 into H2 and solid carbon. However, its application is constrained by the need for efficient heat delivery to the cataly...

Background: While the S-enantiomer of Ketamine (S-Ketamine) is described to be more potent than the racemic form (Ra-Ketamine), with a shorter half-life and almost no side effects, both forms have never been compared in ...

The role of Ukraine on the global geopolitical stage from 1991 to 2025 is analyzed. Based on geopolitical conclusions drawn from the works of scholars such as H. Mackinder and Zb. Brzezinski, the geostrategic importance ...

Fil: Ferreira, Arthur Arruda Leal. Universidad Federal do Rio de Janeiro; Brasil. Fil: Correia, Eduardo Bazilio Gomes. Universidad Federal do Rio de Janeiro; Brasil. Fil: Magalhães, Juliana De Moura Quaresma. Universida...

El objetivo de este trabajo es "(...) estudiar a larga escala cómo la eficiencia energética puede responder a las necesidades del cambio climático y abastecimiento energético, y también de estudiar la implementació...

Materias / palabras clave: Materials science; Epoxy; Composite material; Isopropyl alcohol; Curing (chemistry); Diglycidyl ether; Acetone; Chemical engineering; Chemistry; Polymer chemistry; Nuclear chemistry; Organic chemistry

AutoDock Vina, a new program for molecular docking and virtual screening, is presented. AutoDock Vina achieves an approximately two orders of magnitude speed-up compared with the molecular docking software previously dev...

We describe the testing and release of AutoDock4 and the accompanying graphical user interface AutoDockTools. AutoDock4 incorporates limited flexibility in the receptor. Several tests are reported here, including a redoc...

A novel and robust automated docking method that predicts the bound conformations of flexible ligands to macromolecular targets has been developed and tested, in combination with a new scoring function that estimates the...

Materias / palabras clave: Silicic acid; Dispersity; Particle size; Suspension (topology); Alkyl; Chemical engineering; Range (aeronautics); Particle (ecology); Materials science; Micrometer; SPHERES; Silicic

Materias / palabras clave: Citation; Economics; Sociology; Library science; Computer science

Materias / palabras clave: Monte Carlo tree search; Computer science; Champion; Artificial neural network; Reinforcement learning; Artificial intelligence; Game tree; Value (mathematics); Search algorithm; Tree (set theory); Deep neural networks; ...

Materias / palabras clave: Champion; Artificial intelligence; Artificial neural network; Reinforcement learning; Computer science; Selection (genetic algorithm); Tree (set theory); Machine learning; Domain (mathematical analysis); Mathematics; Pol...