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Randomised controlled trial comparing antibiotic cement bead pouch versus negative pressure wound therapy for the management of severe open tibia fracture wounds: Beads versus VAC (BvV) protocol
Artículo
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Randomised controlled trial comparing antibiotic cement bead pouch versus negative pressure wound therapy for the management of severe open tibia fracture wounds: Beads versus VAC (BvV) protocol
David Sanders et al · BMJ Publishing Group · 2026 · ISSN 2044-6055
Introduction Early open fracture management aims to minimise the risk of complications. For the most severe open fracture wounds, multiple irrigation and debridement surgeries are required to overcome severe wound contam...
LCC LCC:MedicineIdioma eng
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Intraoperative endoscopic pylorus dilatation during minimally invasive Ivor Lewis oesophagectomy to prevent delayed gastric conduit emptying (DGCE): protocol for the WIDE randomised controlled trial
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Intraoperative endoscopic pylorus dilatation during minimally invasive Ivor Lewis oesophagectomy to prevent delayed gastric conduit emptying (DGCE): protocol for the WIDE randomised controlled trial
Jennifer M Klasen et al · BMJ Publishing Group · 2026 · ISSN 2044-6055
Introduction Oesophageal cancer has a poor prognosis and oesophagectomy has increasingly adopted minimally invasive techniques, but delayed gastric conduit emptying (DGCE) still occurs in ~10–50% of patients, depending...
LCC LCC:MedicineIdioma eng
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Patients before paperwork: a feasibility study evaluating digital and human scribes in psychiatric clinical settings – a randomised controlled trial protocol
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Patients before paperwork: a feasibility study evaluating digital and human scribes in psychiatric clinical settings – a randomised controlled trial protocol
Jitender Sareen et al · BMJ Publishing Group · 2026 · ISSN 2044-6055
Introduction There are national calls for reducing physician administrative burden. While interest in digital scribes (DS) is growing, there is limited evidence evaluating their safety and effectiveness. In contrast, hum...
LCC LCC:MedicineIdioma eng
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Adjuvant short-course radiotherapy combined with chemotherapy and a PD-1 inhibitor for resected mucosal melanoma: study protocol for a single-arm, prospective, phase II trial
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Adjuvant short-course radiotherapy combined with chemotherapy and a PD-1 inhibitor for resected mucosal melanoma: study protocol for a single-arm, prospective, phase II trial
Yan Wang et al · BMJ Publishing Group · 2026 · ISSN 2044-6055
Introduction Mucosal melanoma (MM) carries a high risk of postoperative relapse and poorer survival than cutaneous disease. Prospective data from China support adjuvant temozolomide–cisplatin (TMZ/DDP) in resected MM, ...
LCC LCC:MedicineIdioma eng
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Adult persons with type 2 diabetes and family engagement in diabetes self-management education and support: what works, for whom, under what circumstances and how? – a realist review protocol
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Adult persons with type 2 diabetes and family engagement in diabetes self-management education and support: what works, for whom, under what circumstances and how? – a realist review protocol
Siobhán O’Connor et al · BMJ Publishing Group · 2026 · ISSN 2044-6055
Introduction Diabetes self-management education and support (DSME/S) programmes must demonstrate effective engagement of family members to achieve diabetes self-management outcomes and well-being of the whole family. The...
LCC LCC:MedicineIdioma eng
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Association between peripheral serotonin levels and postoperative delirium in older adults undergoing gastrointestinal surgery: a single-centre, prospective cohort study protocol
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Association between peripheral serotonin levels and postoperative delirium in older adults undergoing gastrointestinal surgery: a single-centre, prospective cohort study protocol
Chuan Guo et al · BMJ Publishing Group · 2026 · ISSN 2044-6055
Introduction Postoperative delirium (POD) is a common and serious postoperative complication, with an incidence of approximately 30% among older adults undergoing gastrointestinal surgery. Serotonin has been implicated i...
LCC LCC:MedicineIdioma eng
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Barriers to and facilitators of paediatric early hearing detection and intervention: protocol for a systematic review and meta-synthesis of qualitative evidence
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Barriers to and facilitators of paediatric early hearing detection and intervention: protocol for a systematic review and meta-synthesis of qualitative evidence
Mehrdad Amir-Behghadami et al · BMJ Publishing Group · 2026 · ISSN 2044-6055
Introduction Early hearing detection and intervention (EHDI) is a crucial public health initiative focused on the prompt identification and management of hearing impairments in children, significantly impacting their com...
LCC LCC:MedicineIdioma eng
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Developing the Hungarian version of the MATCH test from the original German language: an evidence-based protocol for the translation, cultural adaptation and validation of paediatric speech audiometry tests from one language into another
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Developing the Hungarian version of the MATCH test from the original German language: an evidence-based protocol for the translation, cultural adaptation and validation of paediatric speech audiometry tests from one language into another
Laszlo Tamas et al · BMJ Publishing Group · 2026 · ISSN 2044-6055
Introduction Speech audiometry is widely used in routine clinical settings to assess auditory function in children. Appropriate test materials are available in languages such as English or German; however, formally valid...
LCC LCC:MedicineIdioma eng
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Efficacy of tegileridine combined with intercostal nerve block for postoperative analgesia following thoracoscopic pulmonary resection: a study protocol for a randomised controlled trial
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Efficacy of tegileridine combined with intercostal nerve block for postoperative analgesia following thoracoscopic pulmonary resection: a study protocol for a randomised controlled trial
Hongbo Zheng et al · BMJ Publishing Group · 2026 · ISSN 2044-6055
Background Patients undergoing thoracoscopic pulmonary resection are prone to moderate-to-severe acute postoperative pain, which not only increases the risk of pulmonary complications but may also lead to chronic postsur...
LCC LCC:MedicineIdioma eng
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Evaluating the impact and cost-benefit of CAMFED’s livelihoods support on young women’s economic activity, health and well-being in Tanzania and Zimbabwe: protocol for a multi-method, longitudinal study
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Evaluating the impact and cost-benefit of CAMFED’s livelihoods support on young women’s economic activity, health and well-being in Tanzania and Zimbabwe: protocol for a multi-method, longitudinal study
Tanya Abramsky et al · BMJ Publishing Group · 2026 · ISSN 2044-6055
Background In sub-Saharan Africa, young women face disproportionate challenges transitioning from school to employment, with high rates of those not in education, employment or training (NEET). Structural barriers—incl...
LCC LCC:MedicineIdioma eng
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Integrating orthotic and prosthetic solutions into disaster risk management: a multimethod study protocol
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Integrating orthotic and prosthetic solutions into disaster risk management: a multimethod study protocol
Hamidreza Khankeh et al · BMJ Publishing Group · 2026 · ISSN 2044-6055
Introduction Disasters often cause large numbers of injuries, including fractures, lacerations and amputations, which overwhelm emergency services. Orthotic and prosthetic solutions can provide timely primary care, reduc...
LCC LCC:MedicineIdioma eng
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Maraviroc for Stroke Recovery (MASTER): protocol for a phase 2 double-blind placebo-controlled randomised clinical trial
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Maraviroc for Stroke Recovery (MASTER): protocol for a phase 2 double-blind placebo-controlled randomised clinical trial
Emmanuel Carrera et al · BMJ Publishing Group · 2026 · ISSN 2044-6055
Introduction Despite advances in acute treatment, stroke remains the first cause of acquired disability. Today, there is no effective pharmacological therapy to improve recovery beyond the acute phase. Preclinical studie...
LCC LCC:MedicineIdioma eng
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Multimodal approach to exploring neighbourhood and transportation dynamics in HIV care in Kenya: protocol
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Multimodal approach to exploring neighbourhood and transportation dynamics in HIV care in Kenya: protocol
Purnima Madhivanan et al · BMJ Publishing Group · 2026 · ISSN 2044-6055
Background HIV is a major health challenge in Kenya, where prevalence exceeds global averages. Achieving viral suppression depends on consistent adherence to antiretroviral therapy (ART), but individuals in neighbourhood...
LCC LCC:MedicineIdioma eng
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Oxytocin substitution therapy in patients with AVP deficiency (central diabetes insipidus): study protocol of a double-blind, randomised placebo-controlled trial
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Oxytocin substitution therapy in patients with AVP deficiency (central diabetes insipidus): study protocol of a double-blind, randomised placebo-controlled trial
Mirjam Christ-Crain et al · BMJ Publishing Group · 2026 · ISSN 2044-6055
Introduction Arginine vasopressin (AVP) and oxytocin (OXT) are both hormones released from the posterior pituitary. While AVP primarily regulates water reabsorption in the kidneys, OXT plays a key role in socioemotional ...
LCC LCC:MedicineIdioma eng
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Psychosocial factors associated with non-suicidal self-injury in Iranian adolescents and young adults: a scoping review protocol
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Psychosocial factors associated with non-suicidal self-injury in Iranian adolescents and young adults: a scoping review protocol
Rahele Dinparvar et al · BMJ Publishing Group · 2026 · ISSN 2044-6055
Introduction Non-suicidal self-injury (NSSI) is defined as the deliberate harm to one’s body without suicidal intent. Although individuals engaging in NSSI do not intend to die, repetitive self-injury may increase the ...
LCC LCC:MedicineIdioma eng
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Safety and efficacy of pharmacological interventions for hepatic outcomes of metabolic dysfunction-associated steatotic liver disease: protocol for systematic review and network meta-analysis
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Safety and efficacy of pharmacological interventions for hepatic outcomes of metabolic dysfunction-associated steatotic liver disease: protocol for systematic review and network meta-analysis
Shirin Djalalinia et al · BMJ Publishing Group · 2026 · ISSN 2044-6055
Introduction Metabolic dysfunction-associated steatotic liver disease (MASLD) is a leading cause of morbidity and mortality due to chronic liver disease. There is an extensive body of evidence focusing on pharmacotherapy...
LCC LCC:MedicineIdioma eng
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The GRACE video-telehealth project protocol: a mixed-methods study to improve quality, safety and acceptability of video-telehealth in Australian general practice and residential aged care
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The GRACE video-telehealth project protocol: a mixed-methods study to improve quality, safety and acceptability of video-telehealth in Australian general practice and residential aged care
Christopher Pearce et al · BMJ Publishing Group · 2026 · ISSN 2044-6055
Introduction Access to safe, high quality, acceptable and sustainable general practice (GP) and primary care services is essential to improved health outcomes and quality of life for people living in residential aged car...
LCC LCC:MedicineIdioma eng
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Understanding LUng Cancer risk factors and their Impact Assessment (LUCIA): protocol for multicentre observational cohort study
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Understanding LUng Cancer risk factors and their Impact Assessment (LUCIA): protocol for multicentre observational cohort study
Hermann Brenner et al · BMJ Publishing Group · 2026 · ISSN 2044-6055
Introduction Lung cancer (LC) is the leading cause of cancer-related mortality worldwide, primarily due to diagnosis at advanced stages. Although low-dose computed tomography (LDCT) screening reduces lung cancer mortalit...
LCC LCC:MedicineIdioma eng
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BronQ Family: assessing the long-term impact of Bronchopulmonary Dysplasia on affected families' health-related quality of life – protocol of a multi-country study
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BronQ Family: assessing the long-term impact of Bronchopulmonary Dysplasia on affected families' health-related quality of life – protocol of a multi-country study
Silke Mader et al · BMJ Publishing Group · 2026 · ISSN 2399-9772
Introduction Bronchopulmonary Dysplasia (BPD) is a frequent chronic complication of preterm birth. While clinical outcomes have been widely studied, evidence on the long-term impact on parents and caregivers – particul...
LCC TENDOlBlZGlhdHJpY3M~Idioma eng
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Integrating users’ perspectives during the development of the Chronic Pain Recommendation Map: protocol for a qualitative descriptive study
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Integrating users’ perspectives during the development of the Chronic Pain Recommendation Map: protocol for a qualitative descriptive study
Gordon Guyatt et al · BMJ Publishing Group · 2026 · ISSN 2044-6055
Introduction One in five people experience chronic pain globally, yet management remains suboptimal and discrepant guideline recommendations are common. To increase pain literacy and improve concordance between evidence ...
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Interaction as care in advanced dementia: protocol for a qualitative video-based study of routine care practices
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Interaction as care in advanced dementia: protocol for a qualitative video-based study of routine care practices
Anca-Cristina Sterie · BMJ Publishing Group · 2026 · ISSN 2044-6055
Introduction Interaction plays a central role in the delivery of care and in supporting participation and well-being in healthcare. For people living with advanced dementia, cognitive and communicative impairments can re...
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