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Interferonopathies are rare autoinflammatory disorders driven by a constitutive upregulation of the type I interferon (IFN-I) pathway, leading to chronic activation of this cytokine. Despite advances, direct IFN-I measur...

ObjectivesParents often lack knowledge regarding healthy sleep practices, and little is known about whether a brief behavioral intervention emphasizing mastery, personalization, motivation, and modeling can increase pare...

Abstract Circumaortic left renal vein (CLRV) is a rare variation in which two renal veins encircle the aorta prior to draining into the inferior vena cava (IVC) and can be classified into three types based on branching p...

Resumo Objetivo Descrever os processos administrativos de fiscalização do Conselho Regional de Enfermagem de Minas Gerais sobre o dimensionamento de pessoal de enfermagem em unidades de internação hospitalar. Mét...

Estudo que teve como objetivo conhecer a atuação do enfermeiro acerca da primeira consulta de puericultura do neonato e identificar quais ações e orientações são realizadas ao neonato e sua família na Unidade Bá...

Abstract The conclusions of the European Food Safety Authority (EFSA) following the peer review of the initial risk assessments carried out by the competent authority of the rapporteur Member State France for the pestici...

High ambient temperatures are associated with a variety of negative outcomes, from exacerbated mental illness to aggression to increased dementia symptoms. One possible proximal mechanism influencing these impacts is hea...

The recognition of disorders of immune dysregulation, particularly those presenting with lymphoproliferation and systemic autoimmunity (International Union of Immunological Societies [IUIS] Group 4.6), has markedly incre...

Although Brazil has experienced substantial immigration from the Middle East and Italy, regions with a higher prevalence of pyrin-associated autoinflammatory diseases, pyrinopathies, remain under-investigated in the coun...

Abstract Purpose To evaluate the clinical impact of the dose to structures not routinely constrained in the radiation treatment (RT) of stage III NSCLC, such as the left anterior descending artery (LAD) and the estimated...

Immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome is a monogenic disorder caused by loss-of-function mutations in the FOXP3 gene, which is critical for the development of functional regulato...

Germline gain-of-function (GOF) variants in the transcription factor STAT3 are associated with early-onset, multisystem autoimmunity, lymphoproliferation, and immune dysregulation. Although STAT3 hyperactivation is a def...